The former Bayer Leverkusen star's fitness will be assessed daily by Liverpool's physiotherapists and medical staff as they attempt to determine whether he can join full training sessions with the rest of the squad.
90 minutes later and things had only gotten worse.
The manager and his players, however, responded in the best way possible.
They chose to strike back.
Emre Can was substituted after just 27 minutes during Liverpool's 5-0 win over Watford at Anfield.
Over the months that followed between these fixtures and the Reds' next Premier League loss - not until January 22nd, away to Swansea - it became evident that Klopp's tactical outlook had shifted.
Marcus Rashford pays lovely tribute to his mum after World Cup call-up
Chelsea's young midfielder Ruben Loftus-Cheek has earned selection after an impressive season on loan at Crystal Palace. Another uncapped player on the plane will be Nick Pope , who was magnificent in front of goal for Burnley this season.
"Sure, we've had to win matches, go step by step, and put in a lot of work to reach the final".
"Don't let your emotions overtake your expectations", Dixon said on the Europa League highlights show when asked how Liverpool should approach the game.
Sessegnon, who can play as a left-winger as well as in the full-back position, scored to send Fulham to the play-off final, after sealing a 2-1 second-leg victory over Derby.
Their Champions League results followed the same trajectory.
"It is my first season in the Champions League and I am one of the leading scorers, alongside Cristiano and Salah".
The Reds are in the hunt for a sixth European crown while rivals Real Madrid are pushing for their third consecutive Champions League title. "The final is set to be a classic and we can't wait to bring it to football fans across the United Kingdom".
"There will be goals at both ends, but it is about who manages the game better".