Mohamed Salah set the new Premier League scoring record, while Dejan Lovren, Andy Robertson, and Dominic Solanke also scored to lead Liverpool back into the UEFA Champions League regardless of the final against Real Madrid.
"Perfect", Liverpool manager Juergen Klopp said.
City's tally ends at 106 goals, ahead of Chelsea's 103 scored in the 2009/10 campaign. The London club finished fifth after a 3-0 loss at Newcastle, in what could prove to be Antonio Conte's last league game as manager. That is what we need. "The boys are humans, not machines".
Guardiola went on to praise City's youngsters Phil Foden and Brahim Diaz who got Premier League winners medals for their contribution this season. "We are progressing and learning from the manager, we have a good chance of winning trophies".
Stoke City, West Brom and Swansea City have been relegated to the Championship.
Swansea paid tribute to long-serving custodians Angel Rangel and Leon Britton before kickoff.
"It's been the hardest season".
"But during the game we were focused, and at the end, an excellent pass from Kevin [De Bruyne] and an awesome finish from Gabriel made the difference and achieved that record". It's been unfortunate, because it's such a great club.
Tottenham beat Leicester 5-4 in the highest-scoring game of the day to secure third place above Liverpool. They also were level at 4 following Jamie Vardy's second of the night when Kane completed his brace.
It also waved goodbye to Arsene Wenger, at least at Arsenal.
City's away points haul is 50 after the Saints win, beating that of Chelsea's 48 in 04/05.
"Do I feel relief?" I would imagine the club have had discussions probably ever since I walked through the door in terms of what they would do.
Trump to Meet North Korea's Kim in Singapore in June
The freed prisoners are in good health, and US officials said they did not find any significant physical or psychiatric concerns. Mr Trump said Kim wants to bring North Korea into "the real world". "Maybe it will [work out], maybe it won't".