Men account for most of the suicide deaths and they make up a huge majority of those with no diagnosed mental issues.
"For many of us who have been close to someone or lost someone we know that suicide happens and that we know it's a real risk out there".
The report calls on state and local communities, health care providers, and individuals to take steps to prevent suicide.
He said the best thing to do if you think someone you know is suicidal is have a conversation with them about how they are doing.
Despite an increased awareness and more help available than ever before, there is still a stigma attached to reaching out for help.
The greatest increase in suicides was seen in "middle-aged adults", between the ages of 45 and 64.
Looking at CDC figures from 2014, suicide is the second leading cause of death among those aged 10-34.
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"It means that around 16 out of every 100,000 Americans will take their own life", the CDC study concluded, according to a report by the British Broadcasting Corporation (BBC).
As suicide becomes more of a public health problem, there are a number of organizations that provide free support for people in need.
Enos said these are people who don't want to die. Among people aged 15 to 34, suicide is the second leading cause of death.
Although suicide is often attributed exclusively to mental health conditions, it is rarely caused by a single factor, the researchers said.
We encourage everyone to get educated about the signs to look for that indicate someone may be in emotional distress.
Dr. Christine Moutier, a psychiatrist and chief medical officer for the American Foundation for Suicide Prevention, said Friday it's important for everyone to know the warning signs and to intervene when family members, friends or co-workers appear troubled.
If you or someone you love needs help, the National Suicide Prevention hotline is 1-800-273-TALK (8255) or text "talk" to 741741.