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Drugs with suicidal symptoms as a possible side effect also went up.

The data used in the study were collected as part of the National Health and Nutrition Examination Survey.

The 200 commonly used medications include birth control pills... blood pressure & heart medications... antacids and painkillers.

Now, a recent study suggests that over-the-counter and prescription medications could be a factor in America's high rates of depression and suicide.

For example, 15 percent who took three or more of these drugs reported depression, compared to 7 percent who took only one drug with ties to the mood disorder, Qato said.

As Americans are living longer with multiple chronic health problems, they're also becoming more likely to take a variety of prescription medications, and the potential for serious or even life-threatening side effects can rise with the number of daily pills.

A team of researchers from the University of IL at Chicago discovered that over 200 general medications put up for sale in the United States contribute depression condition as possible undesirable effect. In the year 2005-2006, 35 percent of the participants had been taking a prescription drug with depression listed as a potential side effect, but less decade a later, in 2013-2014, this figure jumped to 38.4 percent.

Similar increases were found with drugs that list suicide as a potential side-effect.

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According to the study, the common prescription medications prescribed don't have anything to do with depression, so that is one reason that patients, and even their health care providers, don't know about the risk, according to University of IL campus online publication, UIC Today.

In addition to these significant figures, about five per cent of the adult population in the United States is suffering from depression. Researchers from the University of IL at Chicago examined 26,000 adult patients from 2005 to 2014. "As a pharmacist, when a patient comes in and reports depressive symptoms, I just think it's really important to think about what other medications they are on".

Researchers cautioned that the survey approach meant conclusions could not be drawn about cause-and-effect, and that questionnaires did not account for a history of depression.

The research is the first to show that these drugs are often used concurrently and that concurrent use, called polypharmacy, is linked to an increased risk of depression.

Most are prescription drugs, but some are available over the counter, Qato said.

The findings are particularly alarming because numerous drugs don't come with warning labels, and are meant for conditions users wouldn't naturally associate with their emotional or mental state.

"For some patients, this may involve revising their medication regimen before initiating an antidepressant or psychotherapy", she said.