Hawking was a generous charitable sponsor and donor, who set up the Stephen Hawking Foundation "to facilitate research into Cosmology, Astrophysics and Fundamental Particle Physics both at school and university level" and also "facilitate and support work relating to Motor Neurone Disease and those living with the disease".
He had said he tried to lead as normal a life as possible without thinking about his condition.
In Season 9's The Celebration Experimentation, Stephen Hawking made another appearance on the show.
Hawking was fascinated by the nature of the universe, why it is as it is, and why it exists at all.
Hawking was known for his work with black holes and relativity, and wrote several books on the topics including bestseller A Brief History of Time.
Stephen William Hawking will live on forever as one of the brightest and most profound scientists to grace the scientific fraternity.
He overcame the disease and became one of, if not the world's greatest living scientist.
At the age of 32, Hawkings earned the Albert Einstein Award due to his Radiation Theory that matter, in the form of radiation, can escape the gravitational force of a collapsed star. He also penned the 1988 best-seller A Brief History of Time, in which he explored questions such as how the universe began, whether it's unending, the flow of time, and more - all in a language the average reader could understand.
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"The NHS must be preserved from commercial interests and protected from those who want to privatise it", he previously said.
"I believe that the long-term future of the human race must be in space", Hawking told CNN's Becky Anderson. I very much like to remember him by pasting below a picture taken during a free-fall flight - a tale-telling proof that he wouldn't resign to his life challenges.
His exceptional contributions to scientific knowledge and the popularisation of science and mathematics left an indelible legacy, University of Cambridge vice chancellor Stephen Toope said: "His character was an inspiration to millions".
When Stephen Hawking discovered the Hawking radiation, he was embarrassed to put it forward because then the general perception was that Black Holes ate up everything that came within the periphery due to their strong gravitational field.
Perhaps the most notable is Eddie Redmayne's portrayal of Hawkings in the film "The Theory of Everything", which got him a Best Actor Oscar win.
In September 2016, Hawking joined 375 "concerned" scientists in penning an open letter criticizing then-presidential candidate Donald Trump, citing the threat of climate change and blasting his push for the U.S. to leave the Paris accord.
Hawking voiced himself three times in the Simpsons - the first one being in 1999 for the episode They Saved Lisa's Brain.
Directed by James Marsh, this was adapted from the memoir Travelling to Infinity: My Life with Stephen by Jane Hawking. The couple divorced in 1991.