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No. 2 overall pick Saquon Barkley made a splash in his National Football League debut Thursday night. In fact, it looked like they were back at Oklahoma and Penn State, respectively, competing for the Heisman Trophy.

His long run went for 19 yards.

Barkley had four more carries, which only resulted in four yards gained, after his big play.

Callaway, the Browns' fourth-round pick, played despite being cited for marijuana possession and driving with a suspended license. Spencer Drago was called for holding, though, setting up third-and-18.

The second of those scampers - a 5-yard, red-zone dash on fourth-and-2 - set up Mayfield's 10-yard touchdown toss to David Njoku.

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It was all so familiar for Sooners fans and novel for Clevelanders.

Replacing starting quarterback Tyrod Taylor late in the first quarter, Mayfield threw two touchdowns in two-plus quarters to help the Browns beat the Giants 20-10 on Thursday night.

Mayfield returned in the third quarter to spin additional magic, rolling to his right on a third-and-7 from his own 22 to find rookie Antonio Callaway along the sideline for 24 yards.

Martin also caught two passes for 11 yards to make for an impressive debut. But this is a different year with a lot of different players.

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