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The Aidan O'Brien-trained horse suffered a fractured shoulder during Tuesday's race and had to be euthanised, Racing Victoria's executive general manager of integrity services, Jamie Stier, said in a statement.

Aside from the weather, another dark cloud on the day was the tragic fate of Irish horse The Cliffsofmoher, which had to be euthanized after sustaining an injury during the race.

THE 2018 Melbourne Cup is fast becoming the most hard year on record to pick a victor with a host of popular online bookmakers crashing just an hour out from the race. The horse was euthanased after the race.

"Ryan (Moore) could have had a fall or someone else could have got injured".

According to the Daily Mail, The Cliffsofmoher was agitated before the start, with one commentator describing the horse as "melting like an ice cream". "He's really sweating up badly".

Regal Monarch, trained by Chris Waller, was euthanised after falling in race four past year, while British stayer Red Cadeaux was put down two weeks after falling and breaking a leg in the 2015 Melbourne Cup.

As for Appleby, who is already contemplating a successful defence of the Melbourne Cup in 12 months time, he was full of praise for McEvoy.

Magic Circle, who finished 17th, was found to have broken a blood vessel, but was recovering well and not in any further danger.

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So important is the race that it is a public holiday in the state where it is held - Victoria - although it has not enjoyed its usual central focus during the annual spring carnival this year.

It has taken 30 years and millions of dollars, but Sheikh Mohammed bin Rashid Al Maktoum can now finally call himself a Melbourne Cup victor.

The Cliffsofmoher's jockey Ryan Moore looks dejected as he walks off the track, while Cross Counter's win in the Melbourne Cup plays on the big screen behind him. He was treated by vets for three weeks after the race, but was eventually euthanised.

In 2014, Admire Rakti, who collapsed and died in his stall after the race, and Araldo, who broke his leg and was euthanased, were casualties.

McEvoy launched himself into rare company with his 2018 win, joining the likes of Glen Boss, Darby Munro and Damien Oliver as jockeys to win three Melbourne Cups.

"Unfortunately these things can happen galloping around the fields at home and it's very sad", O'Brien said.

The area was drenched with more than 46mm of rain falling on Flemington before 2.30pm (NZT), prompting fears jockeys and horses were at risk of injury.