Manchester United, who beat Paris Saint-Germain in dramatic fashion in the last 16, have been drawn to face the daunting prospect of Barcelona in the quarter-finals.
The Reds overcame the Portuguese champions en route to reaching the final in Kiev in 2017-18 at the last-16 stage, winning the first leg emphatically by scoring five times without reply at the Estadio do Dragao.
Their defence has improved immeasurably since Virgil van Dijk moved to Anfield in January 2018, with the Dutchman's impressive performances now seeing him rated as one of the best central defenders in the world.
With four Premier League teams in the quarter-final, it was highly likely that we got an all English clash and it's Pep versus Poch in the last eight and what will surely be a mouth-watering affair.
English hopes are high that this could be their year in Europe's elite club competition after all four of their representatives made it through to the last eight.
Former Liverpool goalkeeper Chris Kirkland was delighted by the draw, telling Sky Sports News: "I'd prefer being at home for the second leg but I'm extremely happy". @ManUtd, " Pique wrote on Twitter.
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Can Ole Solksjaer keep up his magic as the Man U manager, or will Lionel Messi and the Barcelona side be too much?
Spurs and Man City's European and Premier League ambitions run through each other.
For Solskjaer, the second leg will bring back memories of the 1999 final, when the Norwegian came off the bench to score a stoppage-time victor for United against Bayern Munich at Barcelona's Camp Nou stadium.
Of late, he's had a bit of an eye for goal - notching two in the recent thrashing of Watford, as well as the vital second goal in the Reds' win over Bayern Munich in the Champions League. Back then, Liverpool won 5-0 in Portugal to start their route to the final. Chelsea is especially happy that its draw of Slavia Prague, who it will not overlook, allows it some flexibility with the Liverpool league fixture sandwiched in between.
Cristiano Ronaldo: The most obvious one.
"I wouldn't like Juventus against Barcelona, it would be something really special in a possible final or semi-final".